| Authors Names, Source, and Year | Type of Study | Research Question/Hypothesis | Methodology/Study Design | Level of Evidence | Description of Subjects and Sample Size | Major Findings |
| Aljohi, Hassan & Gupta.
Urology Annals 2016 |
Randomized, single-centered, prospective study. | Does the use of noble metal alloy and hydrogel-coated catheter, compared to a standard catheter for the prevention of CAUTI? | Randomized controlled trial. Single-blinded, randomized, single-centered, prospective investigation. Sixty patients, thirty with the use of noble metal alloy and thirty with the use of hydrogel-coated catheter, compared to a standard catheter. | B | Sixty patients (thirty per group), between the ages of 19 and 99 in the Intensive Care Unit (ICU). 30 males and 30 females. | Results demonstrate a 90% (P = 0.006) relative reduction in the noble metal alloy catheter group of the CAUTI rate. Ten cases of CAUTI were recorded in the standard catheter group while only one case of CAUTI occurred in the noble metal alloy catheter group. |
| Bayar, Ilgi, Dondar, Kirecci, Dalkilinc
Indian Journal of Medical Research and Pharmaceutical Sciences 2014
|
Randomized Controlled Trail. | What is the efficacy of cranberry using for to treatment of urinary tract infection on chronic indwelling urethral catheter patients? | Change urethral catheter once a month as 18 Fr catheter made by silicon material and urine bag every week. Then used ciprofloxacin, trimethoprim-sulfamethoxazole and cefpodoxime for treatment symptomatic CAUTI according to sensitivity tests on first and second steps. Cranberry was suggested to patients, when urinary culture sensitivity tests were reported resistance to last used antibiotics. | B | Seven patients. Six males, and one female. Mean age was 81 years (66-92). | Urinary culture was positive all of patients
after least two different antibiotic treatments. Urinary cultures were positive on four patients after cranberries treatment. |
| Authors Names, Source, and Year | Type of Study | Research Question/Hypothesis | Methodology/Study Design | Level of Evidence | Description of Subjects and Sample Size | Major Findings |
| Cai, Caola, Tessarolo, Piccoli, D’Elia, Caciagli, Nollo, Malossini, Nesi, Mazzoli, Bartoletti
World Journal of Urology 2014 |
Randomized controlled trial of outpatients attending the department between January and June 2010. | Is the use of a preparation with solidago, orthosiphon, birch and cranberry extracts efficient in reducing microbial colonization and biofilm development in patients with indwelling urinary catheters? | A sample size of 10-40 participants per group was considered adequate. All patients underwent urine culture the same day of the catheter substitution and were then randomized into test group (n = 48) and control group (n = 35). Ultrastructural analysis was also performed. After 30 days, the catheter was replaced, and the analysis repeated. The primary outcome was the rate of positive urinary culture at the end of the entire study period. | B | Sample size of 43 test group and 30 control group. | The use of solidago, orthosiphon, birch and cranberry extracts resulted in a significant reduction of microbial colonization in patients with indwelling urinary catheters. |
| Muramatsu, Fujino, Kubo, Otani, Fushimi, & Matsuda
Journal of Epidemiology 2018
|
Cross-sectional studies design for Japanese patients with acute management of cerebral infarction and had used at least an indwelling urethral catheter. | Does antimicrobial catheters protect against CAUTI in cerebral infarction patients? | Data obtained from a Japanese database and performed multi-level logistic regression analysis to analyze the reduction in CAUTI using antimicrobial catheters. | C | 27,548 patients from the Japanese Diagnosis Procedure Combination Database who had been admitted from April 1, 2012 through March 31, 2014 for acute management of cerebral infarction and had used at least an indwelling urethral catheter. | The incidence rate of CAUTI in the antimicrobial catheter group was not significantly less than that of the standard catheter group. However, the results suggested that antimicrobial catheters did reduce CAUTI incidence in diabetic patients who are treated with insulin. |
| Saint, Greene, Damschroder, & Krein,
National Institutes of Health 2013
|
Descriptive or Survey Research Design. Mailed survey to multiple hospitals’ infection control department. | Is the Use of Antimicrobial Devices to Prevent Infection Correlated Across Different Healthcare-Associated Infections? | Using a national sample of non-federal hospitals, the study surveyed infection prevention personnel to understand how often their hospital used specific practices to prevent CAUTI, CLABSI, and ventilator-associated pneumonia (VAP). | A | Mailed survey to a total of 588 non-federal hospitals. A total of 406 hospitals responded for an overall response rate of 69%. | For CAUTI, antimicrobial urinary catheters were reported to be regularly used in 45% of hospitals. |
| Sorour, Nuzzo, Tuttle, Naidus, Donovan, Bekhit, & … Fabrizio,
Canadian Journal of Infection Control 2016
|
Case-Controlled Study about incidence of CAUTI in the Critical Care Unit (CCU) and the general wards (GW). | Is the implementation of a hospital-based program of cranberry products (CP) and application of topical antimicrobials to the urinary meatus effective in the prevention of CAUTI? | Data of Foley days and incidence of CAUTI in the Critical Care Unit (CCU) and the general wards (GW) in a single 245-bed suburban medical center were
collected as a part of routine infection control surveillance. Standard CAUTI prevention bundles were applied throughout the hospital in 2009. In May 2012 an intervention of applying Bacitracin ointment to the urinary meatus-Foley junction and oral cranberry juice or tablets was started only in the CCU.
|
C | No demographic or patient data were collected. | Data indicate that the addition of cranberry-containing products and antimicrobial meatal care may further reduce incidence of CAUTI when added to standard recommendations. Further research will be necessary to determine if these interventions could be effective in a wider population. |
References
Alanood Ahmed, A., Hanan Elkefafy, H., & Rakesh Kumar, G. (2016). The efficacy of noble metal alloy urinary catheters in reducing catheter-associated urinary tract infection. Urology Annals, Vol 8, Iss 4, Pp 423-429 (2016), (4), 423. doi:10.4103/0974-7796.192099 Available from: http://www.urologyannals.com/text.asp?2016/8/4/423/192099
Bayar, G., Musab Ilgi, Cigdem Dondar, Sinan Levent Kirecci, Ayhan Dalkilinc (September 2014). CRANBERRY FRUIT USING FOR TO TREATMENT SYMPTOMATIC URINARY TRACT INFECTION ON INDWELLING URETHRAL CATHETER PATIENTS. Indian Journal of Medical Research and Pharmaceutical Sciences. Vol 1, ISS 4. Retrieved April 07, 2018, from http://www.ijmrps.com/Issues%20PDF/Vol.1/September- 2014/2_Cranberry%20Fruit%20Using%20For%20To%20Treatment%20Sympto matic%20Urinary%20Tract%20Infection%20On%20Indwelling%20Urethral%20 Catheter%20Patients.pdf
Cai, T., Caola, I., Tessarolo, F., Piccoli, F., D’Elia, C., Caciagli, P., . . . Bartoletti, R. (2014, August). Solidago, orthosiphon, birch and cranberry extracts can decrease microbial colonization and biofilm development in indwelling urinary catheter: A microbiologic and ultrastructural pilot study. Retrieved April 04, 2018, from https://www.ncbi.nlm.nih.gov/pubmed/24092275
Muramatsu, K., Fujino, Y., Kubo, T., Otani, M., Fushimi, K., & Matsuda, S. (2018). Efficacy of Antimicrobial Catheters for Prevention of Catheter-Associated Urinary Tract Infection in Acute Cerebral Infarction. Journal of Epidemiology, 28(1), 54–58. http://doi.org/10.2188/jea.JE20170022
Saint, S., Greene, M. T., Damschroder, L., & Krein, S. L. (2013). Is the Use of Antimicrobial Devices to Prevent Infection Correlated Across Different Healthcare-Associated Infections? Results from a National Survey. Infection Control and Hospital Epidemiology: The Official Journal of the Society of Hospital Epidemiologists of America, 34(8), 847–849. http://doi.org/10.1086/671269
Sorour, K., Nuzzo, E., Tuttle, M., Naidus, E., Donovan, L. M., Bekhit, M., & … Fabrizio, P. (2016). Addition of bacitracin and cranberry to standard Foley care reduces catheter-associated urinary tract infections. Canadian Journal of Infection Control, 31(3), 166-168.
